Journal article
Analyses of compact Trichinella kinomes reveal a MOS-like protein kinase with a unique N-terminal domain
AJ Stroehlein, ND Young, PK Korhonen, BCH Chang, PW Sternberg, G La Rosa, E Pozio, RB Gasser
G3 Genes Genomes Genetics | GENETICS SOCIETY AMERICA | Published : 2016
Abstract
Parasitic worms of the genus Trichinella (phylum Nematoda; class Enoplea) represent a complex of at least twelve taxa that infect a range of different host animals, including humans, around the world. They are foodborne, intracellular nematodes, and their life cycles differ substantially from those of other nematodes. The recent characterization of the genomes and transcriptomes of all twelve recognized taxa of Trichinella now allows, for the first time, detailed studies of their molecular biology. In the present study, we defined, curated, and compared the protein kinase complements (kinomes) of Trichinella spiralis and T. pseudospiralis using an integrated bioinformatic workflow employing ..
View full abstractRelated Projects (2)
Grants
Funding Acknowledgements
Research funding from the National Health and Medical Research Council (NHMRC), Australian Research Council, Wellcome Trust, and The University of Melbourne Business Improvement Program is gratefully acknowledged (R.B.G.). Support from the Australian Academy of Science, the Australian-American Fulbright Commission, Alexander von Humboldt Foundation, and Melbourne Water Corporation, as well as the Victorian Life Sciences Computation Initiative and WormBase (www.wormbase.org), is gratefully acknowledged. P.W.S. acknowledges support from the Howard Hughes Medical Institute and the National Institutes of Health. A.J.S. is a recipient of a Melbourne International Research Scholarship and a Melbourne International Fee Remission Scholarship from the University of Melbourne. N.D.Y. holds an NHMRC Career Development Fellowship.